To lessen the potential risk of respiratory melancholy, appropriate dosing and titration of DILAUDID INJECTION is critical [see DOSAGE AND ADMINISTRATION]. Overestimating the DILAUDID INJECTION dosage when converting clients from A different opioid product may end up in a lethal overdose with the initial dose.

Hazard of respiratory melancholy is best through initiation of therapy or subsequent a dosage maximize; observe clients intently for respiratory despair, especially inside of very first 24-seventy two hr of initiating therapy and pursuing dosage improves

This drug could result in drowsiness, dizziness, or impair imagining or motor capabilities; clients need to keep away from driving or operating equipment until eventually adverse consequences are decided.

No significant conversation is expected with concurrent use of opioid analgesics and alvimopan in clients who received opioid analgesics for seven or fewer consecutive times prior to alvimopan.

asenapine transdermal and hydromorphone the two improve sedation. Steer clear of or Use Alternate Drug. Restrict use to people for whom different cure selections are have a peek here insufficient

fentanyl iontophoretic transdermal procedure and hydromorphone equally increase sedation. Keep away from or Use Alternate Drug. Limit use to sufferers for whom alternative treatment options are insufficient

Ensure precision when prescribing, dispensing, and administering oral Solution; dosing errors resulting from confusion in between mg and mL may result in accidental overdose and Demise

Opioid tolerant sufferers only (prolonged-launch:) 8-64 mg PO qDay; may well administer a beginning dose comparable to affected individual's overall everyday oral hydromorphone dose administered after day by day with or without foods

If opioid use is necessary for a chronic period inside a Expecting girl, suggest the have a peek at this web-site affected individual of the chance of neonatal opioid withdrawal syndrome and make sure that suitable therapy might be obtainable.

Serotonin syndrome: Situations of serotonin syndrome, a likely daily life-threatening problem, have been reported for the duration of concomitant use of opioids with serotonergic medications.

If the response to an opioid antagonist is suboptimal or only brief in nature, administer supplemental antagonist as this content directed because of the product's prescribing info.

Constantly consult your Health care company to make certain the information exhibited on this site applies to your own conditions.

Reserve concomitant prescribing of these this contact form prescription drugs in sufferers for whom other treatment selections are insufficient. Limit dosages and durations to your minimal expected. Observe closely for signs of respiratory despair and sedation.

Don't adjust your this content dose. Get DILAUDID specifically as prescribed by your Health care company. Use the lowest dose probable to the shortest time required.